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Bone Marrow Transplant
Bone Marrow Transplant In India: Connect With the Best Hospitals and Top Specialists
Numerous blood cancer patients, including those with leukaemia, lymphoma, sickle cell disease, and other fatal illnesses, rely on bone marrow or cord blood transplants. This is also known as BMTs, which helps in prolonging lives.
The supple, spongy tissue found inside bones is called bone marrow. The majority of the body’s blood cells grow and are kept there.
Stem cells are the blood cells that produce other blood cells. The pluripotent stem cell is the most basic type of stem cell. Given below characteristics set this blood cell apart from others:
- Renewal: It can create an additional cell that is an exact replica of itself.
- Differentiation: It has the capacity to produce one or more subgroups of better-developed cells.
Remember, Stem cells are necessary in a bone marrow transplant.
What Is Bone Marrow Transplant?
A bone marrow transplant is a treatment to replace diseased bone marrow with healthy marrow, which is found inside the bones where your body produces and stores blood cells.
A stem cell transplant is another name for a bone marrow transplant. Hematopoietic stem cells, which are relatively immature cells, are the precursors of your blood cells. When they reach adulthood, they leave your bone marrow and enter your blood.
A transplant can treat several conditions, including malignant cancers. Damaged bone marrow produces insufficient immune system cells and not enough blood cells. It also entails a protracted healing period and the potential for some side effects. If you want to learn more about Bone marrow transplants in India, Med Tours Advisors can assist you to connect with the top surgeon today.
Why is it done?
As mentioned above, a bone marrow transplant is intended to treat a variety of illnesses, including cancer. This treatment may be required when the chemotherapy or radiation dosages required to treat cancer are so high that the patient’s bone marrow stem cells may be irreparably harmed or destroyed by the treatment. If a condition has destroyed the bone marrow, BMTs may also be required.
Given below are a few conditions where one may require a bone marrow transplant:
- In place of unhealthy, dysfunctional bone marrow, use healthy bone marrow that is functioning (for conditions such as leukaemia, aplastic anaemia, and sickle cell anaemia).
- It helps in replacing bone marrow with genetically healthy functioning bone marrow that further prevents damage from a genetic disease process like adrenoleukodystrophy.
- Rebuild a new immune system that will combat leukaemia that is already present or that has not been completely eradicated by the chemotherapy or radiation used during the transplant.
- After high doses of chemotherapy and/or radiation are applied to treat a tumour, replace the bone marrow and return it to its healthy functioning. A common name for this procedure is rescuing.
What Are The Benefits Of BMT?
Some of the benefits of undergoing a BMT are:
- The only available treatment for Hodgkin’s and Non-lymphoma Hodgkin’s is BMT.
- BMT helps in curing Thalassemia, Chronic Myeloid Leukaemia, Aplastic Anaemia, and many other genetic disorders.
- Even though myeloma cannot be entirely cured, BMT can be recommended as the first line of treatment because it dramatically improves survival rates.
- BMT is advised in the event of leukaemia to improve the likelihood of a cure.
Bone Marrow Transplant Types
The following are the many types of BMT treatment approaches:
1. Autologous Bone Marrow Transplantation:
Autologous Bone Marrow Transplantation is a procedure in which the patient’s own bone marrow is transplanted. High-dose, intense chemotherapy or radiation therapy is used to treat cancer. Your cells and immune response may be harmed as a result of this procedure. This is why surgeons take or save your cells from your blood or bone marrow before commencing medical care.
After chemotherapy, the cells are restored to the human body, rebuilding your immune system and also your potential to create blood cells and fight infection.
2. Allogeneic bone marrow transplant:
In this bone marrow transplantation, another individual, referred to as a donor, is used to extract cells. In most circumstances, the donor’s DNA must at least match yours. Special tests assess if a donor is a good match for you.
A person with blood relations is considered the perfect match. Parents, children, and other relatives might occasionally make a suitable match.
3. Umbilical cord blood transplant:
Allogeneic transplantation is a term used to describe a procedure in which a person receives organs from another person. Cells are removed from a newborn baby’s umbilical cord shortly after delivery. The bone cells are frozen and stored until they are needed for a transplant.
Perfect matching isn’t required because umbilical cord blood cells are so young. Because of the delay, blood counts take substantially longer to recover.
Procedure
How You Prepare: Know About the Procedure
Pretransplant tests and proceduresa
A range of tests and procedures can evaluate your general health and the state of your condition. Additionally, the examinations and treatments make sure that you are fit and healthy for the transplantation. The assessment could take a few days or longer.
A lengthy, thin tube (intravenous catheter) will also be placed into a significant vein in your neck or chest. The catheter, which is sometimes referred to as a central line, is often left in place during your therapy. The transplant team will use the central line to inject drugs, blood components, and the transplanted stem cells into your body.
Collecting stem cells for autologous transplant
If an autologous transplant (using your own stem cells) is intended, you will go through a process called apheresis to obtain blood stem cells.
You will be given daily growth factor injections prior to apheresis to promote the creation of more stem cells and to help them enter your bloodstream so that they can be removed.
Blood is taken from a vein and circulated via a machine during apheresis. The machine divides your blood into many components, including stem cells. To be used in the transplant in the future, these stem cells are harvested and frozen. Blood that is left over is reabsorbed by your body.
Stem cell collection for allogeneic transplant
You’ll need a donor if you’re getting an allogeneic transplant, which uses stem cells from a donor. Stem cells are extracted from a donor when one has been identified for the transplant.
Blood or bone marrow from your donor may include stem cells. Your transplant team will decide which is better for you depending on your circumstances.
The Conditioning Process
You will start a process called conditioning after finishing the pretransplant exams and procedures. You will receive chemotherapy and perhaps radiation treatment while you are conditioned to:
–Â If you are being treated for cancer that could spread to other parts of your body, eliminate malignant cells, Suppress your immune system
– Get your bone marrow ready to receive the new stem cells.
Your overall health, including the disease being treated and the sort of transplant you are getting, will all influence the type of conditioning procedure you get. As part of your conditioning treatment, you might have radiation in addition to chemotherapy or only one of these treatments alone.
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What you can expect ?
While undergoing a bone marrow transplant:
Your bone marrow transplant occurs after you complete the conditioning process. Stem cells are led into your body through your central line on the day of your transplant. The infusion for the transplant is painless. Throughout the procedure, you will be awake.
After a bone marrow transplant:
Your blood transports the fresh stem cells to your bone marrow after they have penetrated your body. They gradually grow in number and start to produce fresh and healthy blood cells. It is also known as engraftment. In general, patients who receive a bone marrow transplant may need a few weeks to recover before leaving the hospital, and follow-up appointments will then last for another three months.
Why choose India for bone marrow transplant?
Doctors and surgeons in India are highly educated and have years of experience treating potentially fatal diseases. Also, India has developed in the field of medicine and research technologies.
The leading hospitals in India are popular in terms of technology and infrastructure. However, there are a few other advantages of Bone marrow Transplants in India, some of which are given below:
- India is an excellent choice for a bone marrow transplant due to its affordability and reliability in the best hospital for bone marrow Transplants.
- Time-limited, exclusive programmes with a few affiliated institutions for patients
- The success rate is high among the best bone marrow transplant hospitals in India.
Bone Marrow Transplant Cost In India
Depending on which BMT operation has been suggested for you, the real cost will vary. Also, other factors might influence costs, such as the hospital you’re choosing, doctors and other facilities. However, the most frequently recommended bone marrow transplant treatments for malignancies or blood diseases are autologous and allogeneic. For more information regarding the cost of Bone Marrow Transplant in India, connect with us today.
India's success rate for bone marrow transplants
The success rate of bone transplants varies from hospital to hospital in India, with a range of 80 to 90% on average. This is a result of incredibly experienced and qualified surgeons, hospitals with advanced equipment, and tight standards for infection control and patient care. Patients who have had an autologous transplant have a relatively low recurrence rate.
How Can Med Tour Advisors Help You?
When planning for a Bone marrow transplant in India, we recommend being prepared for every small detail to avoid any surprises.
Connect with us today if you’re looking for the best hospitals & surgeons for a bone marrow transplant. We at Med Tour Advisors will assist you in finding safe & economic doctors for your treatment. From assisting you with the right accommodation solution to arranging your transportation, we are with you at every stage. Our team of experts will not let you down. Visit us today to discover India’s best health care services at affordable prices.
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FAQ
Individuals who receive a Bone Marrow Transplant should expect to be discharged from the hospital within a few weeks, with three months of follow-up appointments.
There are various perks of choosing the best hospital for Bone marrow transplants in India. Some of the facilities are private medical care, emergency & trauma care, lab test, diagnostics, accommodations, critical care units, and many more. All these benefits make India stand out for the best health care treatments.
You can start working out as soon as your bone marrow transplant is successful. However, it’s wise to begin slowly and increase the intensity of the workout as you improve. You can design an exercise regimen specific to your needs and preferences with the help of your healthcare physician.
Yes. Some people might not be eligible for a bone marrow transplant because they are not in good enough health. Because of this, medical professionals take a lot of time to make sure you’re physically ready for a bone marrow transplant. Because the procedure is so physically demanding, it is best to maintain general healthiness before attempting it.
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